Hydroxypropyl Methylcellulose Acetate Succinate-Based Spray-Dried Dispersions: An Overview
نویسندگان
چکیده
منابع مشابه
Hydroxypropyl methylcellulose in drug delivery
Hydroxy propyl methyl cellulose can be used in the development of different drug delivery technology. Nowadays it is a widely used polymer and different viscosity grade of this polymer is available. The hydrophilic and hydrophobic form (both variants) of this polymer is also available. This study includes a review of this polymer on use in different drug delivery system mosty focusing on more r...
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A six-month repeated-dose dermal toxicity study fo11owed by a 30-day recovery test of hydrophobically modified hydroxypropyl methylcellulose (HM-HPMC), a new ceLlulose derivative used as a thickener for topical pharmaceuticals, was conducted using rats, Aqueous paste of HM-HPMC was applied to the skin ofrats once daily at dose levels up to 60 mg/kglday, which was the highest dose that could be ...
متن کاملSolid-state, triboelectrostatic and dissolution characteristics of spray-dried piroxicam-glucosamine solid dispersions.
This work explores the use of both spray drying and d-glucosamine HCl (GLU) as a hydrophilic carrier to improve the dissolution rate of piroxicam (PXM) whilst investigating the electrostatic charges associated with the spray drying process. Spray dried PXM:GLU solid dispersions were prepared and characterised (XRPD, DSC, SEM). Dissolution and triboelectric charging were also conducted. The resu...
متن کاملSpray-Dried Lactose
pray-dried (SD) lactose was introduced to the pharmaceutical market in the 1960s as an excipient that enables direct compression of formulations in a simple manufacturing process (1). To this day, lactose remains one of the most popular excipients for active pharmaceutical ingredients (APIs) whose dose makes them suitable for direct compression. Several manufacturers make and sell SD lactose, a...
متن کاملPupil size and reactivity following hydroxypropyl methylcellulose and sodium hyaluronate.
AIMS A prospective randomised clinical trial was set up to compare the effect of hydroxypropyl methylcellulose (Ocucoat) and sodium hyaluronate (Healonid) on pupil size and reactivity following their use in cataract surgery. METHODS Pupil measurements were recorded before and 6 weeks after surgery. RESULTS There was no significant difference between the two groups with respect to pupil size...
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ژورنال
عنوان ژورنال: Molecular Pharmaceutics
سال: 2008
ISSN: 1543-8384,1543-8392
DOI: 10.1021/mp8000793